THE major heart problem for cats is HCM, hypertrophic cardiomyopathy. For some purebreds, namely Maine coons and American shorthairs, there is a clear genetic component. With Maine coons, they ate looking for a second gene even. But it is a disease that can strike any cat from my posh persians to my moggies. And 50% of the time there are no symptoms.
For a thorough article on it, please read:
http://www.manhattancats.com/Articles/Hypertrophic_Cardiomyopathy.html
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